TargetNeuronal acetylcholine receptor subunit alpha-9(RAT)
National Institute On Drug Abuse
Curated by PDSP Ki Database
National Institute On Drug Abuse
Curated by PDSP Ki Database
TargetNeuronal acetylcholine receptor subunit alpha-9(RAT)
National Institute On Drug Abuse
Curated by PDSP Ki Database
National Institute On Drug Abuse
Curated by PDSP Ki Database
TargetNeuronal acetylcholine receptor subunit alpha-9(RAT)
National Institute On Drug Abuse
Curated by PDSP Ki Database
National Institute On Drug Abuse
Curated by PDSP Ki Database
TargetNeuronal acetylcholine receptor subunit alpha-9(RAT)
National Institute On Drug Abuse
Curated by PDSP Ki Database
National Institute On Drug Abuse
Curated by PDSP Ki Database
TargetNeuronal acetylcholine receptor subunit alpha-9(RAT)
National Institute On Drug Abuse
Curated by PDSP Ki Database
National Institute On Drug Abuse
Curated by PDSP Ki Database
TargetNeuronal acetylcholine receptor subunit alpha-9(RAT)
National Institute On Drug Abuse
Curated by PDSP Ki Database
National Institute On Drug Abuse
Curated by PDSP Ki Database
TargetNeuronal acetylcholine receptor subunit alpha-9(RAT)
National Institute On Drug Abuse
Curated by PDSP Ki Database
National Institute On Drug Abuse
Curated by PDSP Ki Database
Affinity DataIC50: 0.390nMAssay Description:Inhibition of rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response incubated for 5 mins in presence o...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response incubated for 5 mins in presence o...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response incubated for 5 mins in presence o...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response incubated for 5 mins in presence o...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-9(RAT)
National Institute On Drug Abuse
Curated by PDSP Ki Database
National Institute On Drug Abuse
Curated by PDSP Ki Database
Affinity DataIC50: 2.40nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor by the displacement of [3H]-nicotine from rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of rat nAChR alpha9alpha10 expressed in Xenopus laevis oocytes holding potential of -70 mV by two electrode voltage-clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Inhibition of rat alpha9alpha10 nAChRMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
Affinity DataIC50: 6.90nMAssay Description:Inhibition of rat alpha9alpha10 nAChRMore data for this Ligand-Target Pair
Affinity DataIC50: 6.90nMAssay Description:Inhibition of recombinant rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current by voltage clamp ...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Antagonist activity at Sprague-Dawley rat alpha9alpha10 nAChR expressed in Xenopus oocytes assessed as inhibition of ACh-induced current by voltage c...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -80 mV holding potential ...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of rat alpha9/alpha10 nAChR expressed in Xenopus oocytes assessed as inhibition of acetylcholine-induced currents after 300 secs by two-el...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of rat alpha9/alpha10 nAChR expressed in Xenopus oocytes assessed as inhibition of acetylcholine-induced currents after 300 secs by two-el...More data for this Ligand-Target Pair
Affinity DataIC50: 109nMAssay Description:Inhibition of rat alpha9alpha10 nAChRMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-9(RAT)
National Institute On Drug Abuse
Curated by PDSP Ki Database
National Institute On Drug Abuse
Curated by PDSP Ki Database
Affinity DataIC50: 110nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor by the displacement of [3H]-nicotine from rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of rat alpha9/alpha10 nAChR expressed in Xenopus oocytes assessed as inhibition of acetylcholine-induced currents after 300 secs by two-el...More data for this Ligand-Target Pair
Affinity DataIC50: 667nMAssay Description:Inhibition of rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-ele...More data for this Ligand-Target Pair
Affinity DataIC50: 875nMAssay Description:Inhibition of rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -80 mV holding potential ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.42E+3nMAssay Description:Inhibition of rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -80 mV holding potential ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -80 mV holding potential ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at rat alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at rat alpha9alpha10 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membrane currents...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current after 2 to 4 days by voltage ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potenti...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potenti...More data for this Ligand-Target Pair
